The Okrika North Archdeaconry (ONA), with its headquarters at Bethel Anglican Church, Amadi-Ama, under the leadership of Late Ven. E. A. Iyaye, rose to the challenge of planting an Anglican Church in Ozuboko-Ama. A class in the community Primary School building was made available for programmes and services.
The ONA Evangelical team conducted evangelical campaigns in Ozuboko-Ama on weekends, climaxing in a victory rally on Sunday, 11th March, 2001 — the first Church Service — led by Ven. E. A. Iyaye. The church was christened St. Andrew's Anglican Church, Ozuboko-Ama, Port Harcourt. A Lay Reader was sent each Sunday by Bethel Anglican Church to preach and direct services. Subsequently, on 1st November, 2002, Mr. Benjamin Inimgba was sent as the first Church Teacher.
In a PCC meeting of Bethel Anglican Church on 12th February, 2003, it was resolved that the name be changed from "St. Andrew's" to St. Luke's Anglican Church, Ozuboko-Ama, due to the potential confusion with the St. Andrew's First African Church nearby. The christening was performed by Ven. Sackay Fiberesima.
In December 2011, the first Baptism of the church took place — five children were baptised. At the Bishop's instance, Bethel Anglican Church and St. Luke's collaborated to purchase a permanent site from Mr. Samuel Iringe-Koko in October 2011. The present temporary building on the permanent site was built within 20 days in January 2012, with the first service held on 22nd January, 2012.
St. Luke's had her first Deacon, Rev'd T. W. Anyanakaye, in 2010 — priested in 2011 — giving the Church a proper place in the affairs of the Diocese.